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[Role of the amygdala in the sedation induced by low doses of apomorphine].
- Source :
-
Bollettino della Societa italiana di biologia sperimentale [Boll Soc Ital Biol Sper] 1983 May 30; Vol. 59 (5), pp. 686-9. - Publication Year :
- 1983
-
Abstract
- In the present study the role of amygdala in the antidepressant action of imipramine is discussed. An animal model of depression is induced, in rats, by systemic injection of low doses of apomorphine. Systemic administration of imipramine prevents, as already reported, apomorphine-induced sedation. The same effect is observed following intra-amygdaloid imipramine administration. On the contrary, local injection of imipramine in frontal cortex or caudate nucleus does not affect apomorphine-induced sedation.
Details
- Language :
- Italian
- ISSN :
- 0037-8771
- Volume :
- 59
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Bollettino della Societa italiana di biologia sperimentale
- Publication Type :
- Academic Journal
- Accession number :
- 6683970