Back to Search
Start Over
Nephrotic syndrome and focal glomerular sclerosis in aging man.
- Source :
-
Nephron [Nephron] 1978; Vol. 20 (6), pp. 307-15. - Publication Year :
- 1978
-
Abstract
- Focal glomerular sclerosis (FGS) with the nephrotic syndrome is a disecades. Less than 2% of reported patients are older than 60 years of age, and to our knowledge no patients over 70 years of age have been described. The present report documents with renal biopsies the occurrence of FGS and the nephrotic syndrome in 4 patients with an average age of 70 years, 3 being septuagenarians. We suggest that FGS in these patients may represent a disease of senescence, and that FGS in younger patients may result from accelerated glomerulotubular senescence.
- Subjects :
- Adult
Age Factors
Aged
Animals
Child
Edema complications
Female
Heart Diseases complications
Humans
Immunoglobulin M analysis
Kidney Glomerulus ultrastructure
Male
Middle Aged
Nephrosclerosis complications
Nephrosclerosis immunology
Nephrotic Syndrome complications
Rats
Kidney Glomerulus pathology
Nephrosclerosis pathology
Nephrotic Syndrome pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1660-8151
- Volume :
- 20
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Nephron
- Publication Type :
- Academic Journal
- Accession number :
- 662049
- Full Text :
- https://doi.org/10.1159/000181259