Back to Search
Start Over
Biochemical analysis of variant HLA-B27 antigens.
- Source :
-
Human immunology [Hum Immunol] 1983 Feb; Vol. 6 (2), pp. 111-7. - Publication Year :
- 1983
-
Abstract
- Biochemical analysis of HLA-B27 antigens from individuals that are HLA-ABC identical by serology but distinct in CML typing establishes that two types of HLA-B27 can be defined biochemically. The division of HLA-B27 into a W type and a K type by CML typing correlates perfectly with the biochemical data. HLA-B27 K type possesses a more basic isoelectric point than HLA-B27 W type. Neuraminidase digestions of immunoprecipitated HLA-A,B antigens establish that the difference in isoelectric point between HLA-B27 K and HLA-B27 W is not due to differences in sialic acid content.
Details
- Language :
- English
- ISSN :
- 0198-8859
- Volume :
- 6
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Human immunology
- Publication Type :
- Academic Journal
- Accession number :
- 6601098
- Full Text :
- https://doi.org/10.1016/0198-8859(83)90067-8