Back to Search Start Over

Regional mapping of hexokinase-1 within the short arm of chromosome 10.

Authors :
Dallapiccola B
Novelli G
Micara G
Delaroche I
Moric-Petrovic S
Magnani M
Source :
Human heredity [Hum Hered] 1984; Vol. 34 (3), pp. 156-60.
Publication Year :
1984

Abstract

Hexokinase-1 (HK1) activity was determined in red cells of 5 patients with partial duplications of chromosome 10, all of which involved the 10p region. In 4 patients the levels of HK1 activity were higher than the mean activity of controls, strongly indicating a triplex dosage effect. The most likely regional assignment for HK1 would appear to be 10p11.2.

Details

Language :
English
ISSN :
0001-5652
Volume :
34
Issue :
3
Database :
MEDLINE
Journal :
Human heredity
Publication Type :
Academic Journal
Accession number :
6590458
Full Text :
https://doi.org/10.1159/000153453