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Effects of phenobarbitone and short-term exposure to heat on microsomal cytochrome P-450 and associated monooxygenases in rat liver.
- Source :
-
Acta physiologica Polonica [Acta Physiol Pol] 1984 Sep-Dec; Vol. 35 (5-6), pp. 546-50. - Publication Year :
- 1984
-
Abstract
- Short-term exposure of the control and phenobarbitone-treated rats to high ambient temperature caused a different response of the hepatic microsomal cytochrome P-450-dependent monooxygenase system participating in the oxidation of aniline, aminopyrine and p-nitroanisole. The highest differences of the enzyme activities were observed in rats exposed to 28 degrees C, as compared with animals exposed to 21 degrees C or 37 degrees C.
Details
- Language :
- English
- ISSN :
- 0044-6033
- Volume :
- 35
- Issue :
- 5-6
- Database :
- MEDLINE
- Journal :
- Acta physiologica Polonica
- Publication Type :
- Academic Journal
- Accession number :
- 6545996