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Dipeptides delay the onset of morphine withdrawal in the mouse.
- Source :
-
Acta physiologica Hungarica [Acta Physiol Hung] 1984; Vol. 63 (1), pp. 83-4. - Publication Year :
- 1984
-
Abstract
- The effect of dipeptides was studied on naloxone-precipitated morphine withdrawal in the mouse. In accordance with previous data, s.c. treatment with Z-prolyl-D-leucine delayed the onset of withdrawal jumpings . Replacement of L-proline by L-glutamate or L-pyroglutamate resulted in dipeptides which were more potent in morphine withdrawal than was Z-prolyl-D-leucine.
Details
- Language :
- English
- ISSN :
- 0231-424X
- Volume :
- 63
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Acta physiologica Hungarica
- Publication Type :
- Academic Journal
- Accession number :
- 6540034