Estimating the recombination frequency for the MN and the Ss loci.

Authors :: Spence MA
Field LL
Marazita ML
Joseph J
Sparkes M
Crist M
Crandall BF
Anderson CE
Bateman JB
Rotter JI
Source :: Human heredity [Hum Hered] 1984; Vol. 34 (6), pp. 343-7.
Publication Year :: 1984
Abstract: Linkage analysis of 146 informative families for MN and Ss resulted in an estimate of the recombination frequency greater than previously reported. Our total is 7 recombinant children out of 467 individuals, including 1 confirmed recombinant (retested and HLA-compatible) and 6 not verified. The 95% confidence interval of our estimate of recombination is 0.0033-0.0167. Our results are compared with two earlier studies.