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Cytopathology of an unusual case of centronuclear myopathy. Light- and electron-microscopic investigations.
- Source :
-
Journal of the neurological sciences [J Neurol Sci] 1981 Jun; Vol. 50 (3), pp. 311-33. - Publication Year :
- 1981
-
Abstract
- The results of enzyme-histochemical and electron-microscopic investigations of a patient with centronuclear myopathy combined with targets, cores and prevalence of type-I fibers are presented. The patient had suffered from perinatal hypoxic brain damage, causing enlargement of the ventricular system, slight frontal atrophy and right-sided hemiparesis. Morphologic investigation of muscle fibers demonstrated dynamic activity of an autophagic system represented by a distinct increase of Golgi components adhering to the nuclear surface. By analysing the lytic events ad their sequences, a postnatal secondary migration of subsarcolemmal nuclei to the central regions of muscle fibers can be postulated.
Details
- Language :
- English
- ISSN :
- 0022-510X
- Volume :
- 50
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of the neurological sciences
- Publication Type :
- Academic Journal
- Accession number :
- 6455504
- Full Text :
- https://doi.org/10.1016/0022-510x(81)90146-5