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Isolation of Bacillus subtilis mutants pleiotropically insensitive to glucose catabolite repression.
- Source :
-
Journal of bacteriology [J Bacteriol] 1984 Mar; Vol. 157 (3), pp. 942-4. - Publication Year :
- 1984
-
Abstract
- A pleiotropic mutant of Bacillus subtilis was isolated which overproduced in the presence of glucose several enzymes whose synthesis is subject to glucose catabolite repression. Examination of intracellular metabolites suggested that the mutation may have resulted in a defect in glycolysis, increasing phosphoenolpyruvate and decreasing pyruvate, 2-ketoglutarate, and oxaloacetate.
- Subjects :
- Aconitate Hydratase biosynthesis
Bacillus subtilis genetics
Bacillus subtilis isolation & purification
Glycolysis
Histidine Ammonia-Lyase biosynthesis
Mutation
Phosphoenolpyruvate metabolism
Pyruvates metabolism
Pyruvic Acid
alpha-Glucosidases biosynthesis
Bacillus subtilis enzymology
Enzyme Repression
Genes, Bacterial
Glucose metabolism
Suppression, Genetic
Subjects
Details
- Language :
- English
- ISSN :
- 0021-9193
- Volume :
- 157
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 6421803
- Full Text :
- https://doi.org/10.1128/jb.157.3.942-944.1984