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[Buschke's scleredema and monoclonal dysglobulinemia: apropos of 3 cases].
- Source :
-
Dermatologica [Dermatologica] 1983; Vol. 166 (5), pp. 240-6. - Publication Year :
- 1983
-
Abstract
- A monoclonal gammopathy was observed in 3 adult patients with long-term and widespread scleredema (Buschke's disease). There was no evidence of multiple myeloma in any patient. The monoclonal immunoglobulin was in every case of the IgG-kappa type. Bence Jones proteinuria was noted in 1 case (kappa). Deposition of monoclonal IgG-kappa in the skin was not detected by immunofluorescence microscopy. These findings and previous reports of 5 cases suggest that diffuse scleredema may be frequently associated with paraproteinemia, but the role of monoclonal immunoglobulins in the pathogenesis of the disease remains to be clarified.
- Subjects :
- Adolescent
Adult
Aged
Bence Jones Protein urine
Electrocardiography
Female
Humans
Male
Middle Aged
Scleredema Adultorum complications
Scleredema Adultorum pathology
Skin pathology
Hypergammaglobulinemia complications
Immunoglobulin G analysis
Immunoglobulin Light Chains analysis
Immunoglobulin kappa-Chains analysis
Scleredema Adultorum immunology
Subjects
Details
- Language :
- French
- ISSN :
- 0011-9075
- Volume :
- 166
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Dermatologica
- Publication Type :
- Academic Journal
- Accession number :
- 6409682