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[Bacampicillin in urinary tract infections tolerance in patients with impaired kidney and liver function].
- Source :
-
Immunitat und Infektion [Immun Infekt] 1984 Nov; Vol. 12 (6), pp. 303-8. - Publication Year :
- 1984
-
Abstract
- The evaluation of a 10-day 3 x 800 mg dosage regimen was equivalent for bacampicillin to oral ampicillin therapy (using 3 or 4 g respectively per day) in patients with primary UTI (n = 50) in clinical and bacteriological respect. The cure rate amounted to 69 and 68,4% respectively 2 days after therapy. No differences could be assessed after a 2-, 4- and 6-week period. Frequency of diarrhoea was 3 times as high in the ampicillin group as in the bacampicillin group. The rate of exanthema was also 2,5 times as high. No differences existed between eosinophilia and pain complaints in the upper gastrointestinal tract. 10 patients with liver function disturbances and renal impairment respectively tolerated well bacampicillin treatment. Only in the patients with impaired liver function rise of BUN and urea was found in 3 cases, not related to rise of creatinine.
- Subjects :
- Ampicillin administration & dosage
Ampicillin therapeutic use
Clinical Trials as Topic
Drug Administration Schedule
Female
Humans
Kidney Failure, Chronic complications
Liver Cirrhosis complications
Male
Middle Aged
Urinary Tract Infections complications
Ampicillin analogs & derivatives
Kidney Diseases complications
Liver Diseases complications
Urinary Tract Infections drug therapy
Subjects
Details
- Language :
- German
- Volume :
- 12
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Immunitat und Infektion
- Publication Type :
- Academic Journal
- Accession number :
- 6392071