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An improved method for collecting breath for the assay of acetaldehyde.
- Source :
-
Alcoholism, clinical and experimental research [Alcohol Clin Exp Res] 1984 May-Jun; Vol. 8 (3), pp. 293-6. - Publication Year :
- 1984
-
Abstract
- An improved method is described for the collection of breath for the subsequent assay of acetaldehyde and other volatile components. Breath is collected in a Pyrex gas-collecting tube sealed at both ends with Teflon taps. Prior to collection or assay of the samples, this tube is heated to 72 degrees C; breath is sampled for assay by piercing a rubber septum on a sideport with the needle of a similarly heated gas-tight syringe, and injected into a gas chromatograph (GC). The advantages of this system are: (1) Avoidance of the artefacts encountered in the assay of acetaldehyde in the blood; (2) suitability for sample collection at a site remote from the GC laboratory; (3) avoidance of sample loss by leakage, contamination, or partitioning into water condensed from breath; and (4) compatibility with a "nondedicated" GC lacking any special gas-collecting circuitry. A typical study of a normal human volunteer is described, demonstrating the rise and fall of the concentration of acetaldehyde and ethanol in the breath following the ingestion of an oral dose of ethanol.
Details
- Language :
- English
- ISSN :
- 0145-6008
- Volume :
- 8
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Alcoholism, clinical and experimental research
- Publication Type :
- Academic Journal
- Accession number :
- 6377947
- Full Text :
- https://doi.org/10.1111/j.1530-0277.1984.tb05514.x