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beta-Lactamase inhibitors.

Authors :
Cartwright SJ
Waley SG
Source :
Medicinal research reviews [Med Res Rev] 1983 Oct-Dec; Vol. 3 (4), pp. 341-82.
Publication Year :
1983

Abstract

In summary, Table XVI shows the inhibition profiles of representative beta-lactamases from each major class of Richmond and Sykes. Either resistance (R) or sensitivity (S) is given as a general guide to the type of compounds likely to inhibit each class. Thus the (qualitative) statements regarding the effectiveness of clavulanic acid can be taken to represent those for the penam sulfones and similarly for MM4550 and the other olivanic acids, carpetimycins, PS series, and asparenomycins. This can also be said of cloxacillin and the other aromatic carboxamido penicillins. Compounds are also included which are specifically or particularly inhibitory to certain beta-lactamases.

Details

Language :
English
ISSN :
0198-6325
Volume :
3
Issue :
4
Database :
MEDLINE
Journal :
Medicinal research reviews
Publication Type :
Academic Journal
Accession number :
6358721
Full Text :
https://doi.org/10.1002/med.2610030402