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[Dynamics of the activity of the normal mouse spleen killers after partial splenectomy].

Authors :
Van'ko LV
Sukhikh GT
Babaeva AG
Iudina NV
Suleĭmanova NS
Source :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1984 Sep; Vol. 98 (9), pp. 331-3.
Publication Year :
1984

Abstract

The activity of natural killers from the mouse spleen was determined by 51Cr clearance from labeled target cells (YAC-1) at different times after resection of the two-thirds of the spleen. In the early periods after operation, there was a decrease in the natural cytotoxic activity of splenocytes followed by a relatively rapid rise for 8 days until the maximum exceeding the cytotoxicity of intact spleen cells was reached. However, the total lytic potential of the regenerating spleen did not return to normal during 28 days.

Details

Language :
Russian
ISSN :
0365-9615
Volume :
98
Issue :
9
Database :
MEDLINE
Journal :
Biulleten' eksperimental'noi biologii i meditsiny
Publication Type :
Academic Journal
Accession number :
6333256