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[Synthesis and preliminary biological investigation of 2,6-diaryl substituted imidazo(1,2-b)-1,3-4-thiadiazoles].
- Source :
-
Il Farmaco; edizione scientifica [Farmaco Sci] 1984 Jul; Vol. 39 (7), pp. 585-98. - Publication Year :
- 1984
-
Abstract
- The synthesis of imidazo [2,1-b]-1,3,4-thiadiazole derivatives and preliminary pharmacological screening are reported. The compounds studied showed mainly antiphlogistic, antipyretic and analgesic activity. From the results it appears that analgesic activity is peripheral.
- Subjects :
- Animals
Anti-Inflammatory Agents, Non-Steroidal pharmacology
Anti-Inflammatory Agents, Non-Steroidal toxicity
Bacteria drug effects
Behavior, Animal drug effects
Chemical Phenomena
Chemistry
Fungi drug effects
Lethal Dose 50
Male
Mice
Rats
Rats, Inbred Strains
Anti-Inflammatory Agents, Non-Steroidal chemical synthesis
Imidazoles chemical synthesis
Thiadiazoles chemical synthesis
Subjects
Details
- Language :
- Italian
- ISSN :
- 0430-0920
- Volume :
- 39
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Il Farmaco; edizione scientifica
- Publication Type :
- Academic Journal
- Accession number :
- 6332744