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Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. II. Serological response.
- Source :
-
The Journal of infectious diseases [J Infect Dis] 1984 May; Vol. 149 (5), pp. 675-82. - Publication Year :
- 1984
-
Abstract
- Serological response to rotavirus and virus shedding were prospectively studied in 179 children (neonatal to 24-month-old) upon admission to a hospital during an 11-month period. Analysis of the evolution of IgG and IgM ELISA titers revealed 24 cases of rotaviral disease (serological response and diarrhea), 13 cases of asymptomatic infection (serological response and no diarrhea), 36 cases of virus carriage (absence of a serological response), three cases of past infection, and six possible cases of nosocomial infection. Rotaviral disease was encountered two out of three times and was characterized by diarrhea associated with fever and vomiting. Asymptomatic rotaviral infection and disease, observed from the neonatal period onwards, affected 2% of neonates, 20% of one- to six-month-old children, and 37% of 7-24-month-old children. In contrast, virus carriage occurred in 27%, 19%, and 14% of those children respectively. Altogether these results indicate that during the period 1-24 months of age, when asymptomatic rotaviral infection and disease were prevalent, approximately two of 10 children had rotaviral disease, one of 10 had asymptomatic infection, two of 10 were virus carriers, and five of 10 were not infected with rotavirus.
- Subjects :
- Aging
Child, Preschool
Cross Infection epidemiology
Enzyme-Linked Immunosorbent Assay
Feces microbiology
Female
Fever etiology
Humans
Immunoglobulin G analysis
Immunoglobulin M analysis
Infant
Infant, Newborn
Male
Prospective Studies
Rotavirus isolation & purification
Rotavirus Infections immunology
Rotavirus Infections microbiology
Vomiting etiology
Antibodies, Viral analysis
Carrier State epidemiology
Rotavirus immunology
Rotavirus Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0022-1899
- Volume :
- 149
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The Journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 6327845
- Full Text :
- https://doi.org/10.1093/infdis/149.5.675