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Phase II trial of m-AMSA in hepatocellular carcinoma: a Southwest Oncology Group Study.
- Source :
-
Cancer treatment reports [Cancer Treat Rep] 1982 Aug; Vol. 66 (8), pp. 1651-2. - Publication Year :
- 1982
-
Abstract
- Twenty-three patients with heptocellular carcinoma were treated with m-AMSA at a dose of 120 mg/m2 iv repeated at 4-week intervals. Toxicity was primarily hematologic. Partial responses occurred in two of 14 previously treated patients and in one of nine previously untreated patients. The overall activity of m-AMSA in patients with hepatocellular carcinoma appears minimal.
- Subjects :
- Adolescent
Adult
Aged
Aminoacridines adverse effects
Amsacrine
Antineoplastic Agents adverse effects
Drug Evaluation
Female
Humans
Leukopenia chemically induced
Male
Middle Aged
Aminoacridines therapeutic use
Antineoplastic Agents therapeutic use
Carcinoma, Hepatocellular drug therapy
Liver Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0361-5960
- Volume :
- 66
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Cancer treatment reports
- Publication Type :
- Academic Journal
- Accession number :
- 6286120