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The effect of high dose medroxyprogesterone acetate on water and salt metabolism in advanced cancer patients.
- Source :
-
Chemioterapia : international journal of the Mediterranean Society of Chemotherapy [Chemioterapia] 1984 Oct; Vol. 3 (5), pp. 327-9. - Publication Year :
- 1984
-
Abstract
- Ten advanced cancer patients (both with hormone-sensitive and non-hormone sensitive tumors) were treated with high dose medroxyprogesterone acetate (MAP, greater than 500 mg/day). We determined body weight, lean body mass, blood pressure, sodium blood level, urinary excretion, and exchangeable sodium pool by the 22Na method before and after treatment. These data seem to exclude a fluid retentive effect for high-dose MAP.
- Subjects :
- Antineoplastic Agents administration & dosage
Female
Humans
Male
Medroxyprogesterone administration & dosage
Medroxyprogesterone pharmacology
Medroxyprogesterone Acetate
Neoplasms drug therapy
Water-Electrolyte Balance drug effects
Antineoplastic Agents pharmacology
Body Water metabolism
Electrolytes metabolism
Medroxyprogesterone analogs & derivatives
Neoplasms metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0392-906X
- Volume :
- 3
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Chemioterapia : international journal of the Mediterranean Society of Chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 6241849