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Cell-biology of ageing. III. Malondialdehyde as an index of free radical reactions in the early senescent mutants of Neurospora crassa and study of the effect of free radical scavengers on malondialdehyde contents.
- Source :
-
Cell biology international reports [Cell Biol Int Rep] 1984 May; Vol. 8 (5), pp. 373-7. - Publication Year :
- 1984
-
Abstract
- Malondialdehyde - a product of lipid peroxidation due to free radical reaction was estimated in the culture filtrates of early senescent mutants of Neurospora crassa and the effects of vitamin E, vitamin C and Sodium selenite (free radical scavengers) in malondialdehyde contents were studied. From the results obtained, it could not be established that increased free radical reaction was the sole factor for the early senescence of all the mutants; and the free radical scavengers had very little effect on the malondialdehyde content of the selected early senescent mutants.
- Subjects :
- Ascorbic Acid pharmacology
Neurospora crassa drug effects
Neurospora crassa genetics
Selenious Acid
Selenium pharmacology
Time Factors
Vitamin E pharmacology
Free Radicals
Malonates metabolism
Malondialdehyde metabolism
Mutation
Neurospora growth & development
Neurospora crassa growth & development
Subjects
Details
- Language :
- English
- ISSN :
- 0309-1651
- Volume :
- 8
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cell biology international reports
- Publication Type :
- Academic Journal
- Accession number :
- 6234997
- Full Text :
- https://doi.org/10.1016/0309-1651(84)90139-5