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Elicitation of natural killer cells in beige mice by infection with vesicular stomatitis virus.
- Source :
-
Infection and immunity [Infect Immun] 1981 Apr; Vol. 32 (1), pp. 204-10. - Publication Year :
- 1981
-
Abstract
- Vesicular stomatitis virus (VSV) infection of beige (bg/bg) mice induced levels of natural killer cytolytic activity comparable to that of uninfected normal bg/+ controls, but considerably less than natural killer activity in VSV-infected bg/+ mice. In contrast, VSV-infected bg/bg and bg/+ mice had essentially equivalent amounts of anti-VSV cytotoxic T-lymphocyte and antibody activity. VSV infection induced comparable levels of interferon in both bg/bg and bg/+ mice. Therefore, the decreased natural killer activity in bg/bg mice could not be attributed to an inability to produce interferon.
- Subjects :
- Animals
Antibodies, Viral biosynthesis
Antilymphocyte Serum pharmacology
Cytotoxicity, Immunologic
Female
Guinea Pigs
H-2 Antigens immunology
Interferons biosynthesis
Killer Cells, Natural immunology
Lymphoma immunology
Male
Mice
Mice, Inbred C57BL
Stomatitis immunology
Vesicular stomatitis Indiana virus immunology
Virus Diseases immunology
Killer Cells, Natural microbiology
Stomatitis microbiology
Virus Diseases microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 0019-9567
- Volume :
- 32
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Infection and immunity
- Publication Type :
- Academic Journal
- Accession number :
- 6163720
- Full Text :
- https://doi.org/10.1128/iai.32.1.204-210.1981