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[Use of human albumin and dextran-70 in extracorporeal circulation. Postoperative function of blood platelets (author's transl)].
- Source :
-
Medicina clinica [Med Clin (Barc)] 1980 Jun 10; Vol. 75 (1), pp. 20-3. - Publication Year :
- 1980
-
Abstract
- Human albumin and dextran 70 were used as volume expanders in extracorporeal circulation in two homogeneous series of patients. Comparative results were statistically processed. No significant differences were observed either to early postoperative bleeding or needed volume of transfused blood. Postoperative complications neither developed in the two groups of patients. The total number of platelets showed a 50 percent decrease in relation to basal extraction figures and those after immediate heparin neutralization. Results of platelet function tests were similar in both series, except for a statistical significant decrease in ADP-induced platelet aggregation in the group with dextran 70. Such decrease, however, was not followed by an increase of postoperative bleeding. Thus, dextran 70 has showed to be a valuable substitute for human albumin in extracorporeal circulation.
- Subjects :
- Albumins pharmacology
Blood Coagulation drug effects
Dextrans pharmacology
Hemorrhage drug therapy
Humans
Platelet Aggregation drug effects
Postoperative Complications drug therapy
Albumins administration & dosage
Blood Platelets drug effects
Dextrans administration & dosage
Extracorporeal Circulation methods
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0025-7753
- Volume :
- 75
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Medicina clinica
- Publication Type :
- Academic Journal
- Accession number :
- 6156367