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[Tumors of the adrenal gland in childhood. Report of 38 patients].
- Source :
-
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen [Chirurg] 1984 Sep; Vol. 55 (9), pp. 569-74. - Publication Year :
- 1984
-
Abstract
- During the past 17 years at the Department für Pediatric Surgery, University of Heidelberg, 38 children aged 1.6 to 14 years were adrenalectomized (unilateral 3.3, bilateral 5). Individual diagnoses were: neuroblastoma 23; pheochromocytoma 5; adrenocortical carcinoma 8; adrenocortical adenoma 4; bilateral nodular hyperplasia 2 cases. Patients with histologically benign lesions are alive and without recurrence more than 5 years after surgery, except one patient who developed Nelson's tumor after bilateral adrenalectomy for Cushing's disease. Of the patients with malignant adrenal tumors 21 died within 18 months after therapy was started, a 7 years old girl with an adrenal carcinoma died after a period of 3.6 years of combined treatment. In most cases of adrenocortical tumors virilization was the prominent feature.
- Subjects :
- Adenoma surgery
Adolescent
Adrenal Gland Neoplasms drug therapy
Adrenalectomy
Adrenergic alpha-Antagonists therapeutic use
Adrenergic beta-Antagonists therapeutic use
Antineoplastic Agents therapeutic use
Carcinoma surgery
Child
Child, Preschool
Combined Modality Therapy
Cushing Syndrome surgery
Female
Humans
Infant
Male
Neuroblastoma surgery
Pheochromocytoma surgery
Prognosis
Adrenal Gland Neoplasms surgery
Subjects
Details
- Language :
- German
- ISSN :
- 0009-4722
- Volume :
- 55
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
- Publication Type :
- Academic Journal
- Accession number :
- 6149894