Back to Search Start Over

Effect of dieldrin on rat liver plasma membrane enzymes.

Authors :
Bandyopadhyay SK
Tiwari RK
Bhattacharyya A
Chatterjee GC
Source :
Toxicology letters [Toxicol Lett] 1982 Apr; Vol. 11 (1-2), pp. 131-4.
Publication Year :
1982

Abstract

Dieldrin, an organochlorine insecticide, when administered orally to male albino rats at a dose of 5 mg/kg body weight/day for 15 days inhibits the enzyme Mg2+ -ATPase and stimulates the activity of 5'-nucleotidase and NADH-dehydrogenase in liver plasma membrane. L-ascorbic acid supplementation offers some protection in relation to the inhibition of Mg2+ -ATPase.

Subjects

Subjects :
Adenosine Triphosphatases metabolism
Animals
Ascorbic Acid pharmacology
Ca(2+) Mg(2+)-ATPase
Cell Membrane enzymology
Liver drug effects
Male
NADH Dehydrogenase metabolism
Nucleotidases metabolism
Rats
Rats, Inbred Strains
Dieldrin pharmacology
Liver enzymology

Details

Language :
English
ISSN :
0378-4274
Volume :
11
Issue :
1-2
Database :
MEDLINE
Journal :
Toxicology letters
Publication Type :
Academic Journal
Accession number :
6124057
Full Text :
https://doi.org/10.1016/0378-4274(82)90117-5
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details