Use of the beta-lactamase inhibitor clavulanic acid in the isolation of auxotrophic mutants of Bacillus licheniformis.

Authors :: Fields PI
Schreier HJ
Saha AL
Bernlohr RW
Source :: Journal of bacteriology [J Bacteriol] 1984 Aug; Vol. 159 (2), pp. 803-4.
Publication Year :: 1984
Abstract: The isolation of auxotrophic mutants of Bacillus licheniformis, a microbe containing constitutive beta-lactamase activity, was found to be facilitated by the addition of clavulanic acid and cefotaxime during enrichment.

Subjects :: Bacillus drug effects
Bacillus genetics
Cefotaxime toxicity
Clavulanic Acid
beta-Lactamase Inhibitors
Bacillus isolation & purification
Clavulanic Acids pharmacology
Mutation

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