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On the interactions of lipids and proteins in the red blood cell membrane.

Authors :
Glaser M
Simpkins H
Singer SJ
Sheetz M
Chan SI
Source :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1970 Mar; Vol. 65 (3), pp. 721-8.
Publication Year :
1970

Abstract

The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements. The results indicate that a substantial fraction of the phospholipids and the proteins of the membranes can change structure independently of one another, suggesting a mosaic pattern for the organization of the lipids and proteins in membranes.

Details

Language :
English
ISSN :
0027-8424
Volume :
65
Issue :
3
Database :
MEDLINE
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
5267150
Full Text :
https://doi.org/10.1073/pnas.65.3.721