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Bone disease in hemodialysis patients with particular reference to the effect of fluoride.
- Source :
-
Canadian Medical Association journal [Can Med Assoc J] 1974 Jun 22; Vol. 110 (12), pp. 1349-53. - Publication Year :
- 1974
-
Abstract
- Forty-one patients on our chronic hemodialysis program were assessed for the degree of progression of bone disease over an average period of 46 months. Seven patients were using a fluoridated dialysate. Four of these seven patients developed a marked increase in osteoid as judged by bone biopsy, while in the nonfluoridated group the amount of osteoid remained within normal limits.In the absence of fluoride, although osteitis fibrosa occurred, it was reversible in 10 out of 12 cases by dihydrotachysterol treatment, and overall there was no evidence of progression of bone disease at the end of the study period.
- Subjects :
- Adult
Alkaline Phosphatase analysis
Biopsy
Bone and Bones pathology
Dihydrotachysterol therapeutic use
Female
Fibrous Dysplasia of Bone diagnostic imaging
Fibrous Dysplasia of Bone drug therapy
Fibrous Dysplasia of Bone etiology
Fibrous Dysplasia of Bone pathology
Fingers pathology
Glomerulonephritis diagnostic imaging
Glomerulonephritis enzymology
Humans
Male
Radiography
Fibrous Dysplasia of Bone chemically induced
Fluorides adverse effects
Glomerulonephritis therapy
Renal Dialysis adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0008-4409
- Volume :
- 110
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Canadian Medical Association journal
- Publication Type :
- Academic Journal
- Accession number :
- 4834525