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Methotrexate in liver and bile after intravenous dosage in man.

Authors :
Creaven PJ
Hansen HH
Alford DA
Allen LM
Source :
British journal of cancer [Br J Cancer] 1973 Dec; Vol. 28 (6), pp. 589-91.
Publication Year :
1973

Abstract

Measurements of methotrexate have been made in the liver and plasma of 4 patients and in the bile and plasma of 1 patient receiving [(3)H]methotrexate. Projections from a theoretical model of concentration of methotrexate in liver are confirmed but projections of biliary excretion are not.

Details

Language :
English
ISSN :
0007-0920
Volume :
28
Issue :
6
Database :
MEDLINE
Journal :
British journal of cancer
Publication Type :
Academic Journal
Accession number :
4783160
Full Text :
https://doi.org/10.1038/bjc.1973.190