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Association of lactoferrin with lysozyme in granules of human polymorphonuclear leukocytes.
- Source :
-
Infection and immunity [Infect Immun] 1972 Nov; Vol. 6 (5), pp. 761-5. - Publication Year :
- 1972
-
Abstract
- Lactoferrin is contained in cytoplasmic granules of human polymorphonuclear leukocytes. Upon centrifugation, it sediments in a band of granules that also contain 50% of the lysozyme activity. This granule class is distinct from others associated with alkaline phosphatase and peroxidase. The granules are latent for lactoferrin as only lysed granules have the capacity specifically to inhibit antigen binding by anti-lactoferrin serum.
- Subjects :
- Animals
Antigen-Antibody Reactions
Antigens
Centrifugation, Density Gradient
Cytoplasmic Granules
Electrophoresis, Disc
Humans
Immune Sera
Iodine Isotopes
Leukocytes enzymology
Leukocytes immunology
Milk Proteins analysis
Milk, Human analysis
Rabbits immunology
Blood Proteins analysis
Leukocytes analysis
Muramidase blood
Subjects
Details
- Language :
- English
- ISSN :
- 0019-9567
- Volume :
- 6
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Infection and immunity
- Publication Type :
- Academic Journal
- Accession number :
- 4673983
- Full Text :
- https://doi.org/10.1128/iai.6.5.761-765.1972