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Aqueous central cavity in aspartate transcarbamylase from Escherichia coli.

Authors :
Evans DR
Warren SG
Edwards BF
McMurray CH
Bethge PH
Wiley DC
Lipscomb WN
Source :
Science (New York, N.Y.) [Science] 1973 Feb 16; Vol. 179 (4074), pp. 683-5.
Publication Year :
1973

Abstract

A three-dimensional x-ray diffraction study of aspartate transcarbamylase to 5.5-angstrom resolution, with the aid of four isomorphous heavy atom derivatives, indicates the presence of a central aqueous cavity approximating an oblate spheroid about 25 by 50 by 50 angstroms in dimension, within a molecule about 90 by 110 by 110 angstroms in largest dimensions.

Details

Language :
English
ISSN :
0036-8075
Volume :
179
Issue :
4074
Database :
MEDLINE
Journal :
Science (New York, N.Y.)
Publication Type :
Academic Journal
Accession number :
4567940
Full Text :
https://doi.org/10.1126/science.179.4074.683