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[Relationship between the minute superslow oscillations and the level of energy supply in brain tissue].
- Source :
-
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova [Fiziol Zh SSSR Im I M Sechenova] 1979 Mar; Vol. 65 (3), pp. 336-43. - Publication Year :
- 1979
-
Abstract
- In animals, an increase in glycolysis intensity and processes of oxidative phosphorylation in the brain correlated with the steady potential shifts within the range of 0--1.0 Hz in the neocortex, dorsal hippocampus, and thalamic nuclei. The neurotropic drug ethymizol revealed two effects depending on the initial functional state of the rabbit: 2.5 mg/kg of the drug enhanced the amplitude of the minute waves in the frontal neocortex and dorsal hippocampus, increasing the metabolic rate in the unsteady period of conditioning, whereas after the fast conditioning the drug rendered background values to the minute oscillations and elongated the extinction of conditioned reflexes. The ethymizol appears to be an unspecific connector.
- Subjects :
- Animals
Brain Chemistry drug effects
Electrophysiology
Extinction, Psychological drug effects
Glucose analysis
Glycogen analysis
Glycolysis drug effects
Lactates analysis
Oxidative Phosphorylation drug effects
Pyruvates analysis
Rabbits
Rats
Time Factors
Brain drug effects
Conditioning, Classical drug effects
Energy Metabolism drug effects
Etimizol pharmacology
Imidazoles pharmacology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0015-329X
- Volume :
- 65
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova
- Publication Type :
- Academic Journal
- Accession number :
- 456652