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Long pyrimidine tracts of L-cell DNA: localization to repeated DNA.

Authors :
Straus NA
Birnboim HC
Source :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1974 Aug; Vol. 71 (8), pp. 2992-5.
Publication Year :
1974

Abstract

Like HeLa DNA, L-cell DNA contains a significant number of unexpectedly long pyrimidine tracts. 1.3% of the thymidine residues of L-cell DNA are found in these long polypyrimidine tracts. Analysis of L-cell DNA fractions with different rates of reassociation indicates that polypyrimidine tracts are associated with "repeated" DNA. Longer pyrimidine tracts appear to have a higher repetition frequency than shorter tracts, and some may be repeated as many as 5 x 10(4) times in L-cell DNA.

Details

Language :
English
ISSN :
0027-8424
Volume :
71
Issue :
8
Database :
MEDLINE
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
4528633
Full Text :
https://doi.org/10.1073/pnas.71.8.2992