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[Mastocyte osteoporosis].

Authors :
Camus JP
Prier A
Lièvre JA
Stephan JC
Laveant C
Source :
Revue du rhumatisme et des maladies osteo-articulaires [Rev Rhum Mal Osteoartic] 1979 Jan; Vol. 46 (1), pp. 29-35.
Publication Year :
1979

Abstract

We present five cases of severe osteoporosis accompanied by a skin and/or bone mastocytosis. The rarity of mastocytosis demonstrates that these cases are not the result of simple coincidence, especially since none of them involves other general of phospho-calcium anomalies that could explain the demineralization. The latter is accompanied by a high level of histaminemia or histaminuria, a non-specific anomaly. Mastocyte osteoporosis involves a great many unknown factors on the physiopathological level, but in practice it is necessary to look for a mastocytosis when confronted with a severe osteoporosis that appears to be primary. Cytostatic treatment (chlorambucil, cyclophosphamide) seems capable of improving the evolution of the bone disease.

Details

Language :
French
ISSN :
0035-2659
Volume :
46
Issue :
1
Database :
MEDLINE
Journal :
Revue du rhumatisme et des maladies osteo-articulaires
Publication Type :
Academic Journal
Accession number :
441665