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Unstable binary capsulated transformants in pneumococcus.
- Source :
-
Journal of bacteriology [J Bacteriol] 1969 Jun; Vol. 98 (3), pp. 1073-9. - Publication Year :
- 1969
-
Abstract
- Through transformation reactions, binary capsulated SI-III strains of pneumococci have been isolated that are unstable and lose the SI capsular genome at high frequency. The instability is caused by the specific mutation in the SIII capsular genome common to all of the unstable strains. In the family of strains studied, the SI capsular genome was integrated into the recipient chromosome in at least two loci: one apparently adjacent to the resident capsular genome and a second some distance from it. A hypothesis is presented to explain the instability of the strains on the basis of redundancy of genetic information.
Details
- Language :
- English
- ISSN :
- 0021-9193
- Volume :
- 98
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 4389232
- Full Text :
- https://doi.org/10.1128/jb.98.3.1073-1079.1969