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Activity of selected penicillins in vitro and in experimental bacterial infections in mice.
- Source :
-
Applied microbiology [Appl Microbiol] 1967 May; Vol. 15 (3), pp. 566-8. - Publication Year :
- 1967
-
Abstract
- The minimal inhibitory concentration and the 50% mouse protective dose for five key penicillins are presented. Such data provide a useful guide in evaluating the activity of new penicillins, in comparison with those already commercially available, and establishes the amounts of antibiotic necessary to obtain a PD(50) for several experimental model infections in mice.
- Subjects :
- Animals
Dicloxacillin pharmacology
Escherichia coli drug effects
Escherichia coli Infections drug therapy
Mice
Proteus drug effects
Proteus Infections drug therapy
Salmonella Infections, Animal drug therapy
Salmonella paratyphi A drug effects
Staphylococcal Infections drug therapy
Staphylococcus drug effects
Streptococcal Infections drug therapy
Streptococcus pneumoniae drug effects
Streptococcus pyogenes drug effects
Ampicillin pharmacology
Cloxacillin pharmacology
Methicillin pharmacology
Oxacillin pharmacology
Penicillin G pharmacology
Penicillins therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0003-6919
- Volume :
- 15
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Applied microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 4382392
- Full Text :
- https://doi.org/10.1128/am.15.3.566-568.1967