Inversion duplication of chromosome 6 with trisomic codominant expression of HLA antigens.

Authors :: Pearson G
Mann JD
Bensen J
Bull RW
Source :: American journal of human genetics [Am J Hum Genet] 1979 Jan; Vol. 31 (1), pp. 29-34.
Publication Year :: 1979
Abstract: Trisomic codominant expression of the HLA antigens was observed in an infant with duplication of a part of 6p occurring as a result of crossing over within a paternally transmitted pericentric inversion. The HLA-A and B loci were linked absolutely with the inversion chromosome in a four generation pedigree.

Subjects :: Adult
Female
HLA Antigens analysis
Humans
Infant
Lymphocytes immunology
Male
Pedigree
Chromosome Inversion
Chromosomes, Human, 6-12 and X
Genes, Dominant
HLA Antigens genetics
Trisomy

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