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Tilorone hydrochloride: mode of action.

Authors :
Mayer GD
Krueger RF
Source :
Science (New York, N.Y.) [Science] 1970 Sep 18; Vol. 169 (3951), pp. 1214-5.
Publication Year :
1970

Abstract

An antiviral serum component is found in mice treated orally with tilorone hydrochloride. The active material fulfills sufficient biological criteria to be classified as an interferon.

Subjects

Subjects :
Administration, Oral
Animals
Antiviral Agents administration & dosage
Blood
Carcinoma
Cell Line
Dactinomycin pharmacology
Dialysis
Encephalomyocarditis virus drug effects
Fluorenes administration & dosage
Laryngeal Neoplasms
Mice
Ribonucleases
Trypsin
Vesicular stomatitis Indiana virus drug effects
Antiviral Agents pharmacology
Fluorenes pharmacology

Details

Language :
English
ISSN :
0036-8075
Volume :
169
Issue :
3951
Database :
MEDLINE
Journal :
Science (New York, N.Y.)
Publication Type :
Academic Journal
Accession number :
4317924
Full Text :
https://doi.org/10.1126/science.169.3951.1214
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