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Interaction of galactosaminoglycan with Neurospora conidia.
- Source :
-
Journal of bacteriology [J Bacteriol] 1974 Nov; Vol. 120 (2), pp. 759-66. - Publication Year :
- 1974
-
Abstract
- The inactivation of Neurospora crassa conidia by galactosaminoglycan isolated from cultures of this organism was followed by measuring colony-forming ability and ability to take up radiolabeled metabolites. When kinetic data on the loss of transport function and on killing were analyzed by use of target theory, it appeared that few "hits" are required for inactivation. However, studies with radio-labeled galactosaminoglycan mucopolysaccharides showed that cells receiving a single lethal hit have approximately 10(5) galactosaminoglycan molecules bound to them.
- Subjects :
- Absorption
Binding Sites drug effects
Carbon Radioisotopes
Galactosamine metabolism
Glucose metabolism
Glycosaminoglycans metabolism
Hydrogen-Ion Concentration
Kinetics
Neurospora crassa drug effects
Proline metabolism
Temperature
Time Factors
Galactosamine pharmacology
Neurospora growth & development
Neurospora crassa growth & development
Polysaccharides pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0021-9193
- Volume :
- 120
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 4281775
- Full Text :
- https://doi.org/10.1128/jb.120.2.759-766.1974