Radiation from tritiated thymidine perturbs the cell cycle progression of stimulated lymphocytes.

Authors :: Pollack A
Bagwell CB
Irvin GL 3rd
Source :: Science (New York, N.Y.) [Science] 1979 Mar 09; Vol. 203 (4384), pp. 1025-7.
Publication Year :: 1979
Abstract: Tritiated thymidine was found to affect the cell cycle progression of phytohemagglutinin-stimulated human lymphocytes. By means of flow cytometry a statistically significant increase in the G2 and M phases of the cell cycle was observed in cultures with low concentrations of tritiated thymidine added 18 hours before the cultures were harvested.

Subjects :: Cell Cycle drug effects
Dose-Response Relationship, Radiation
Humans
Mitosis radiation effects
Phytohemagglutinins pharmacology
Thymidine pharmacology
Time Factors
Cell Cycle radiation effects
Lymphocyte Activation radiation effects
Lymphocytes radiation effects
Tritium

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