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Ascorbic acid supplementation in the treatment of pressure-sores.
- Source :
-
Lancet (London, England) [Lancet] 1974 Sep 07; Vol. 2 (7880), pp. 544-6. - Publication Year :
- 1974
-
Abstract
- In a prospective double-blind controlled trial the effect of large doses of ascorbic acid on the healing of pressure-sores has been assessed. 20 surgical patients were studied, the pressure areas being assessed by serial photography and ulcer tracings. The mean ascorbic-acid levels in treated and non-treated groups one month after the start of treatment were 65.6 and 25.8 mug per 10-8 white blood-cells. In the group treated with ascorbic acid there was a mean reduction in pressure-sore area of 84% after one month compared with 42.7% in the placebo group. These findings are statistically significant (P less than 0.005) and suggest that ascorbic acid may accelerate the healing of pressure-sores.
- Subjects :
- Aged
Arthritis, Rheumatoid surgery
Ascorbic Acid administration & dosage
Ascorbic Acid blood
Ascorbic Acid pharmacology
Ascorbic Acid Deficiency complications
Cerebrovascular Disorders surgery
Clinical Trials as Topic
Female
Fractures, Bone surgery
Humans
Leukocytes analysis
Male
Middle Aged
Paraplegia complications
Postoperative Complications
Pressure Ulcer blood
Pressure Ulcer diagnosis
Pressure Ulcer etiology
Pressure Ulcer prevention & control
Prospective Studies
Vascular Diseases surgery
Wound Healing drug effects
Ascorbic Acid therapeutic use
Pressure Ulcer drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0140-6736
- Volume :
- 2
- Issue :
- 7880
- Database :
- MEDLINE
- Journal :
- Lancet (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 4140267
- Full Text :
- https://doi.org/10.1016/s0140-6736(74)91874-1