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Histamine augments leukocyte adenosine 3',5'-monophosphate and blocks antigenic histamine release.
- Source :
-
Science (New York, N.Y.) [Science] 1971 Aug 20; Vol. 173 (3998), pp. 743-5. - Publication Year :
- 1971
-
Abstract
- Extracellular histamine stimulates accumulation of adenosine 3',5'-monophosphate in human leukocytes and prevents antigenic release of histamine from cells of allergic donors. Both effects occur at histamine concentrations that can be achieved by antigenic release of the amine in vitro.
- Subjects :
- Adenine metabolism
Adenosine Monophosphate metabolism
Antigens
Depression, Chemical
Humans
Hypersensitivity metabolism
In Vitro Techniques
Leukocytes metabolism
Plants
Stimulation, Chemical
Tritium
Adenine Nucleotides metabolism
Histamine pharmacology
Histamine Release drug effects
Leukocytes drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0036-8075
- Volume :
- 173
- Issue :
- 3998
- Database :
- MEDLINE
- Journal :
- Science (New York, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 4105490
- Full Text :
- https://doi.org/10.1126/science.173.3998.743