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Parietal cell vagotomy in the surgical treatment of chronic duodenal, pyloric and prepyloric ulcer disease.
- Source :
-
International surgery [Int Surg] 1985 Apr-Jun; Vol. 70 (2), pp. 139-44. - Publication Year :
- 1985
-
Abstract
- During the 1970s, parietal cell vagotomy (PCV) gradually became accepted as a suitable method in the surgical treatment of prepyloric, pyloric and duodenal ulcer disease. This study reports the data from a study of 405 consecutive patients with chronic ulcer disease treated with PCV. Mortality was low (0.5%) and there were few postoperative sequelae (periodic loose stools in 2% and mild dumping in 2%). Reduction in basal acid output was 75% and in pentagastrin stimulated acid secretion 50%. The ulcer recurrence rate was initially higher in pyloric-prepyloric (PU/PPU) than in duodenal ulcer disease but after the seventh postoperative year this difference was no longer statistically significant. The accumulated recurrence rate was 17.5%. Few side effects and a comparatively low recurrence rate makes PCV the method of choice in the surgical treatment of peptic ulcer disease.
Details
- Language :
- English
- ISSN :
- 0020-8868
- Volume :
- 70
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- International surgery
- Publication Type :
- Academic Journal
- Accession number :
- 4055278