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[Detection by the immunoenzymatic test ELISA of IgM anti-Cysticercus cellulosae antibodies in the cerebrospinal fluid in neurocysticercosis].
- Source :
-
Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 1985 Mar; Vol. 43 (1), pp. 22-8. - Publication Year :
- 1985
-
Abstract
- IgM antibodies against Cysticercus cellulosae in the cerebrospinal fluid (CSF) was demonstrated by ELISA immunoenzymatic assay in neurocysticercosis. CSF samples of 41 patients were analyzed for this purpose. Diagnosis was neurocysticercosis in 26 and neurosyphilis in 5; abnormalities were not registered in the other 10 cases. Neurosyphilis samples and no-abnormalities samples were considered as control groups. ELISA IgM assay for cysticercosis was negative in all CSF samples of control groups and it was positive in 12 of the 26 CSF samples of the neurocysticercosis group (46.2%). Titers ranged from 4 till 32. Positive results were no more obtained after previous treatment of CSF samples by 2-mercaptoethanol. ELISA IgM and IgG titers were compared. IgM titers wee higher than IgG titers in two cases. Results obtained were compared to those found through complement fixation, immunofluorescence and hemagglutination tests for the diagnosis of neurocysticercosis.
- Subjects :
- Enzyme-Linked Immunosorbent Assay
Humans
Immunoglobulin G cerebrospinal fluid
Neurosyphilis cerebrospinal fluid
Serologic Tests
Central Nervous System Diseases cerebrospinal fluid
Cysticercosis cerebrospinal fluid
Cysticercus immunology
Immunoglobulin M cerebrospinal fluid
Taenia immunology
Subjects
Details
- Language :
- Portuguese
- ISSN :
- 0004-282X
- Volume :
- 43
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Arquivos de neuro-psiquiatria
- Publication Type :
- Academic Journal
- Accession number :
- 4015434
- Full Text :
- https://doi.org/10.1590/s0004-282x1985000100004