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[Pediatric autoimmune digestive diseases].

Authors :
Von-Graffenried T
Karemera M
Pampori E
Thorens Borgeat M
Nydegger A
Rock NM
Source :
Revue medicale suisse [Rev Med Suisse] 2025 Feb 19; Vol. 21 (906), pp. 314-319.
Publication Year :
2025

Abstract

In pediatric gastroenterology and hepatology, autoimmune diseases, such as inflammatory bowel diseases, celiac disease, and autoimmune hepatitis, are challenging for practitioners due to their increasing incidence, high morbidity, and substantial impact on children's quality of life. These conditions share similar pathophysiological mechanisms, including genetic predisposition, the role of the microbiome, and the influence of environmental and immunological factors. This review aims to explore their pathophysiology, diagnostic strategies, treatments, and future perspectives. It highlights the importance of early and multidisciplinary management to improve outcomes for affected children.<br />Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.

Details

Language :
French
ISSN :
1660-9379
Volume :
21
Issue :
906
Database :
MEDLINE
Journal :
Revue medicale suisse
Publication Type :
Academic Journal
Accession number :
39976139
Full Text :
https://doi.org/10.53738/REVMED.2025.21.906.314