[Biogenic amine content of brain sections, blood and adrenals of rabbits exposed to vibration and noise].

Phasic changes of biogenic amines were revealed in brain structures after isolated action of vibration; 15-min vibration increased the content of catecholamines in the hypothalamus and decreased the content of serotonin. 30-min vibration decreased the amount of biogenic amines in the hypothalamus and the cortex. Vibration of a longer duration (1 hr) increased the amount of catecholamines in the brain. After 2-hr vibration the content of catecholamines returned to the control level but the concentration of serotonin still remained above it. Combined action of vibration and noise (2 hrs) decreased the content of catecholamines and increased the amount of serotonin in cerebral structures. Dopamine and serotonin tended to decrease in the blood and adrenals whereas in the urine their amount increased. Multiple combined action of vibration and noise induced the most obvious changes.