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The Fit Older Adult with Acute Myeloid Leukemia: Clinical Challenges to Providing Evidence-Based Frontline Treatment.
- Source :
-
Blood [Blood] 2025 Jan 24. Date of Electronic Publication: 2025 Jan 24. - Publication Year :
- 2025
- Publisher :
- Ahead of Print
-
Abstract
- Recent advances in acute myeloid leukemia (AML) come from studies investigating younger (age<60 years) adults or older (ageā„75 years) or less fit adults. Uncertainty exists for the management of otherwise healthy adults with AML in their 60s and 70s, which also represents a significant proportion of AML cases. We discuss current considerations in older, fit adults with AML including determination of fitness, what factors beyond fitness should be assessed, and finally what challenges and innovations lie ahead to improve outcomes for these patients.<br /> (Copyright © 2025 American Society of Hematology.)
Details
- Language :
- English
- ISSN :
- 1528-0020
- Database :
- MEDLINE
- Journal :
- Blood
- Publication Type :
- Academic Journal
- Accession number :
- 39854694
- Full Text :
- https://doi.org/10.1182/blood.2024026004