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Epigenetic Regulation Via Electrical Forces.

Authors :
McCaig CD
Source :
Reviews of physiology, biochemistry and pharmacology [Rev Physiol Biochem Pharmacol] 2025; Vol. 187, pp. 251-272.
Publication Year :
2025

Abstract

Multiple epigenetic modulations occur to chromatin rather than to DNA itself and these influence gene expression or gene silencing profoundly. Both the creation of these post-translational modifications and the mechanisms of their readout are regulated significantly by electrical forces several of which are discussed. They are also influenced by phase separation which itself is driven by electrical forces.<br /> (© 2025. The Author(s), under exclusive license to Springer Nature Switzerland AG.)

Details

Language :
English
ISSN :
0303-4240
Volume :
187
Database :
MEDLINE
Journal :
Reviews of physiology, biochemistry and pharmacology
Publication Type :
Academic Journal
Accession number :
39838016
Full Text :
https://doi.org/10.1007/978-3-031-68827-0_15