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Porcine cardiac bioprostheses: evaluation of long-term results in 990 patients.
- Source :
-
The Annals of thoracic surgery [Ann Thorac Surg] 1985 Mar; Vol. 39 (3), pp. 243-50. - Publication Year :
- 1985
-
Abstract
- Clinical results with porcine bioprostheses were reviewed for 990 patients who underwent heart valve replacement from January, 1974, to December, 1980. Eight hundred and seventy-four Hancock, 283 Carpentier-Edwards, and 10 Liotta bioprostheses were used. In 23 patients, 26 mechanical prostheses were implanted as well. Overall operative mortality was 60 out of 990 (6.06%): 30 out of 506 (5.9%) for mitral valve replacement (MVR), 13 out of 287 (4.5%) for aortic valve replacement (AVR), 1 out of 4 (25%) for tricuspid valve replacement, 0 out of 2 for pulmonary valve replacement, and 16 out of 191 (8.4%) for multiple valve replacement. Cumulative follow-up covered 1,793 patient-years. (Actuarial survival at 7 years was 76.6 +/- 3% for MVR. At 6 years, it was 83.2 +/- 2.8% for AVR and 55 +/- 13.5% for multiple valve replacement.) Prosthesis-related survival at 7 years was 91.7 +/- 1.9% for MVR, and at 6 years, it was 96.6 +/- 1.5% for AVR and 95.1 +/- 2.2% for multiple valve replacement. Bioprosthesis survival, considering deaths or complications that led to reoperation as final events, was 84.2 +/- 3.7% at 7 years for mitral valves and 87.7 +/- 3.8% at 6 years for aortic valves. Emboli per 100 patient-years numbered 3.2 for MVR, 0.5 for AVR, and 1.6 for multiple valve replacement. Twenty-seven patients underwent reoperation, 12 for perivalvular leak, 5 for endocarditis, 6 for valve thrombosis, and 4 for primary tissue failure (linearized rates of 0.7, 0.3, 0.3, and 0.2% per patient-year, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
- Subjects :
- Adolescent
Adult
Aged
Aortic Valve surgery
Endocarditis etiology
Equipment Failure
Female
Follow-Up Studies
Hemorrhage etiology
Humans
Male
Middle Aged
Mitral Valve surgery
Reoperation
Thromboembolism etiology
Bioprosthesis adverse effects
Bioprosthesis mortality
Heart Valve Prosthesis adverse effects
Heart Valve Prosthesis mortality
Subjects
Details
- Language :
- English
- ISSN :
- 0003-4975
- Volume :
- 39
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Annals of thoracic surgery
- Publication Type :
- Academic Journal
- Accession number :
- 3977465
- Full Text :
- https://doi.org/10.1016/s0003-4975(10)62587-8