Extending Amyloidosis Diagnosis: A Rare Case of Peritoneal AL Amyloidosis Revealed by 18F-FDG PET/CT and 99mTc-PYP SPECT/CT.

Authors :: Arslan DF
Inal E
Isik EG
Sanli Y
Source :: Clinical nuclear medicine [Clin Nucl Med] 2024 Dec 06. Date of Electronic Publication: 2024 Dec 06.
Publication Year :: 2024
Publisher :: Ahead of Print
Abstract: Abstract: We present a case with systemic amyloidosis secondary to immunoglobulin light-chain amyloidosis (AL amyloidosis), which 18F-FDG PET/CT and 99mTc-PYP scintigraphy revealed amyloid deposition in the peritoneum, omentum, and mesentery. AL amyloidosis is characterized by the proliferation of clonal plasma cells and increased production and extracellular accumulation of immunoglobulin light chains, leading to organ malfunction. Even though AL amyloidosis can affect the gastrointestinal system, peritoneal involvement is rarely observed. PET/CT and SPECT/CT images showed moderate to slightly increased tracer uptake in affected organs.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

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