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Drug delivery using gold nanoparticles.

Authors :
Dykman L
Khlebtsov B
Khlebtsov N
Source :
Advanced drug delivery reviews [Adv Drug Deliv Rev] 2025 Jan; Vol. 216, pp. 115481. Date of Electronic Publication: 2024 Nov 29.
Publication Year :
2025

Abstract

Modern nanotechnologies provide various possibilities for efficiently delivering drugs to biological targets. This review focuses on using functionalized gold nanoparticles (GNPs) as a drug delivery platform. Owing to their exceptional size and surface characteristics, GNPs are a perfect drug delivery vehicle for targeted and selective distribution. Several in vitro and in vivo tests have shown how simple it is to tailor these particles to administer chemical medications straight to tumors. The GNP surface can also be coated with ligands to modify drug release or improve selectivity. Moreover, the pharmacological activity can be enhanced by using the photothermal characteristics of the particles.<br />Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1872-8294
Volume :
216
Database :
MEDLINE
Journal :
Advanced drug delivery reviews
Publication Type :
Academic Journal
Accession number :
39617254
Full Text :
https://doi.org/10.1016/j.addr.2024.115481