Genomic analysis and characterization of a new Salmonella phage vB_Sen_ST2 infecting Salmonella enterica serovars Typhi and Typhimurium.

Authors :: Rodea M GE
González-Villalobos E
Espinoza-Mellado MDR
Hernández-Chiñas U
Eslava-Campos CA
Balcázar JL
Molina-López J
Source :: Microbial pathogenesis [Microb Pathog] 2025 Jan; Vol. 198, pp. 107178. Date of Electronic Publication: 2024 Nov 27.
Publication Year :: 2025
Abstract: In this study, we have characterized and sequenced the whole genome of a new member of the Kuttervirus genus, Salmonella phage vB&#95;Sen&#95;ST2. This phage selectively targets Salmonella enterica serovars Typhi and Typhimurium, which are major etiologic agents of salmonellosis worldwide. Its genome consists of a linear, double-stranded DNA of 156,028 bp, with a G + C content of 44.93 %. Based on our results, Salmonella phage vB&#95;Sen&#95;ST2 presents suitable features to be considered as a potential control agent against Salmonella enterica serovars that are responsible for salmonellosis.<br />Competing Interests: Declaration of competing interest The authors declare that there are not conflict of interest.<br /> (Copyright © 2024. Published by Elsevier Ltd.)

Subjects :: DNA, Viral genetics
Genomics methods
Sequence Analysis, DNA
Phylogeny
Whole Genome Sequencing
Host Specificity
Genome, Viral
Salmonella typhi virology
Salmonella typhi genetics
Salmonella Phages genetics
Salmonella Phages isolation & purification
Salmonella Phages classification
Base Composition
Salmonella typhimurium virology
Salmonella typhimurium genetics

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